Comparative study on quality of life between patients with ulcerative colitis and Crohn's disease
溃疡性结肠炎与克罗恩病患者生存质量对比研究

摘要

目的 在中医补土理论下，探讨溃疡性结肠炎（UC）与克罗恩病（CD）患者在生存质量上存在的差异。方法 于本院2018年12月-2019年12月收治的UC与CD患者中，分别选取64例、52例为研究对象，整理出所有患者的病历资料，包括年龄、性别等基本信息，在炎症性肠病生存质量问卷(IBDQ)、情绪自评量表、一般健康状况问卷(SF-36)各量表的应用下，完成患者生存质量的评估与比较。结果 从患者的生理职能、全身症状、情感功能、IBDQ总分等各维度的评分比较上来看，CD患者占据明显优势，差异具有统计学意义（P<0.05）。结论 从中医补土的角度上进行分析，CD患者的病理机制主要与太阴脾虚有关，病情的变化并不会对患者的生存质量造成太大的影响。对UC患者的病理机制进行分析，主要与阴血分受邪有关，伴随着病情的变化，患者的症状表现较为显著，对患者的生存质量有着较大的影响，故两者存在显著差异。

Abstract

Objective: To explore the differences in the quality of life between patients with ulcerative colitis (UC) and Crohn's disease (CD) under the theory of TCM nourishing soil.
Methods: Among the UC and CD patients admitted in our hospital from December 2018 to December 2019, 64 cases and 52 cases were selected as the research objects, and the medical records of all patients, including basic information such as age and gender, were compiled. Under the application of the inflammatory bowel disease quality of life questionnaire (IBDQ), emotional self-assessment scale, and general health status questionnaire (SF-36), the evaluation and comparison of patients' quality of life were completed.
Results: From the comparison of the scores of the patients' physiological function, systemic symptoms, emotional function, IBDQ total score and other dimensions, CD patients had a clear advantage, and the difference was statistically significant (P <0.05).
Conclusion  : From the perspective of TCM nourishing soil, the pathological mechanism of CD patients is mainly related to Taiyin and spleen deficiency, and the change of the disease condition will not have a great impact on the quality of life of patients. The analysis of the pathological mechanism of UC patients is mainly related to the evil of Yin and blood. With the change of the disease, the symptoms of the patients are more significant, which has a greater impact on the quality of life of the patients.