Clinical observation on the efficacy of skin care combined with functional exercises in patients with systemic sclerosis
系统性硬化症患者皮肤护理联合功能锻炼的临床疗效观察

摘要

目的 探究皮肤护理联合功能锻炼对SSc患者皮肤功能、关节活动能力及生活质量的疗效。方法 纳入本院2024年1月-2025年10月100例SSc患者，随机分观察组与对照组各50例。对照组行常规治疗 + 基础护理，观察组加用规范化皮肤护理联合个性化功能锻炼，干预6个月。比较两组干预前后mRSS评分、关节活动度、皮肤屏障指标及SF-36评分。结果 观察组干预后mRSS评分、经皮水分流失量均低于对照组，手部关节活动度、6分钟步行距离、角质层含水量及 SF-36 各维度评分均优于对照组（P均＜0.001）。结论 该联合干预可减轻SSc患者皮肤硬化，改善皮肤屏障与关节功能，提升生活质量，临床价值显著。

Abstract

Objective To explore the efficacy of skin care combined with functional exercise on skin function, joint mobility, and quality of life in patients with systemic sclerosis (SSc).
Methods A total of 100 patients with SSc admitted to our hospital from January 2024 to October 2025 were enrolled and randomly divided into an observation group and a control group, each consisting of 50 cases. The control group received routine treatment plus basic nursing, while the observation group received standardized skin care combined with personalized functional exercise. The intervention lasted for 6 months. The mRSS scores, joint range of motion, skin barrier indicators, and SF-36 scores before and after intervention in the two groups were compared.
Results After intervention, the mRSS scores and transepidermal water loss in the observation group were lower than those in the control group, while the hand joint range of motion, 6-minute walking distance, stratum corneum water content, and all dimensions of the SF-36 score were superior to those in the control group (P < 0.001).
Conclusion   This combined intervention can alleviate skin hardening in patients with SSc, improve skin barrier function and joint function, and enhance quality of life, thus having significant clinical value.