A prospective study on the implementation of aerobic exercise intervention in patients with metabolism-related fatty liver disease
代谢相关脂肪性肝病患者有氧运动干预实施的前瞻性研究

摘要

目的 探讨有氧运动干预在代谢相关脂肪性肝病患者的应用效果，为临床精准干预提供高级别证据。方法 选取2024年2月至2025年2月期间在本院就诊的200例代谢相关脂肪性肝病患者，随机分2组，对照组采用常规生活方式干预，实验组在对照组基础上结合有氧运动干预，即常规生活方式干预+运动处方+监督打卡，比较两组干预效果。结果 实验组BMI、腰围、GPT/ALT、GOT/AST、GGT、LDH、FPG、HbA1c、TC、TG、LDL-C、CAP、E值、SBP、DBP低于对照组，HDL-C高于对照组，组间对比差异显著（P＜0.05）。结论 有氧运动干预在代谢相关脂肪性肝病患者的应用效果明显，可改善患者血脂、血糖、血压、肝功能等指标。通过微信群监督打卡管理方式具备操作简便、易于推行的显著优势，患者接受度高。

Abstract

Objective To explore the application effect of aerobic exercise intervention in patients with metabolism-related fatty liver disease and provide high-level evidence for precise clinical intervention.
Methods A total of 200 patients with metabolism-related fatty liver disease who visited our hospital from February 2024 to February 2025 were selected and randomly divided into two groups. The control group received conventional lifestyle intervention, while the experimental group received aerobic exercise intervention on the basis of the control group, that is, conventional lifestyle intervention + exercise prescription + supervision check-in. The intervention effects of the two groups were compared.
Results The BMI, waist circumference, GPT/ALT, GOT/AST, GGT, LDH, FPG, HbA1c, TC, TG, LDL-C, CAP, E value, SBP and DBP in the experimental group were lower than those in the control group, while HDL-C was higher than that in the control group. The differences between the groups were significant (P < 0.05).
Conclusion   The application effect of aerobic exercise intervention in patients with metabolism-related fatty liver disease is obvious, which can improve the indicators such as blood lipid, blood glucose, blood pressure and liver function of patients. The management method of supervising check-ins through wechat groups has significant advantages such as simple operation and easy implementation, and is highly accepted by patients.