A comparative study on the effects of different disinfectants in neonatal umbilical cord care
新生儿脐部护理中不同消毒剂效果对比研究

摘要

目的 探究75%乙醇、0.5%碘伏与3%双氧水在新生儿脐部护理中的疗效，评估其对脐带脱落、感染防控以及炎症反应造成的影响。方法 挑选180例新生儿，随机分成三组，分别采用三种护理方案，比较脐带脱落、干燥时间以及感染和红肿的发生率，同时检测IL - 6、CRP、WBC等炎症指标和微生物清除效果。结果 碘伏组的脐带脱落与干燥时间最短，感染和红肿的发生率最低，炎症方面的指标明显比乙醇组低，清除微生物的效果比乙醇好，家长满意度最高；双氧水组里真菌定植的情况比较多。结论 0.5%碘伏对新生儿脐部护理成效最优，可加快脐带脱落，减少感染与炎症状况，提高护理满意度，临床应用价值高。

Abstract

Objective To explore the efficacy of 75% ethanol, 0.5% iodophor and 3% hydrogen peroxide in neonatal umbilical cord care, and to evaluate their effects on umbilical cord shedding, infection prevention and control, and inflammatory response.
Methods 180 neonates were randomly divided into three groups and treated with three different care regimens. The time to umbilical cord shedding and drying, the incidence of infection and redness, and inflammatory markers such as IL-6, CRP, and WBC were compared. The microbial clearance effect was also evaluated.
Results The iodophor group had the shortest time to umbilical cord shedding and drying, the lowest incidence of infection and redness, significantly lower inflammatory markers than the ethanol group, better microbial clearance effect than ethanol, and the highest parental satisfaction. The hydrogen peroxide group had more cases of fungal colonization.
Conclusion   0.5% iodophor is the most effective in neonatal umbilical cord care, accelerating umbilical cord shedding, reducing infection and inflammation, and improving care satisfaction. It has high clinical application value.