Application of EN in postoperative chemotherapy for ovarian cancer
EN在卵巢癌术后化疗中的应用

摘要

背景 近年来，卵巢癌患者逐年上升，且五年内的生存率仅为20%-30%，有研究指出40%-80%的癌症患者伴有不同程度的营养不良，约20%肿瘤患者直接死于营养不良仅5%的非主观体重丢失也会导致生存率的降低营养不良肿瘤患者的5年生存率显著低于没有营养不良的患者，因此提高卵巢癌术后熟料患者的营养管理至关重要。目的 探讨EN在可以改善卵巢癌术后化疗患者的胃肠道功能,提高患者的免疫力。结果 肠内营养支持治疗可以改善卵巢癌术后化疗的患者人体测量值、生化指标、免疫功能，减少化疗副作用，因此及时给予EN治疗，可以提高患者免疫力、营养状态，又可以改善患者的生存质量和生存率，并且可以预防化疗毒副反应等并发症的发生，对肿瘤患者的预后有非常积极重要的意义。结论 EN治疗可以改善患者的胃肠道功能,提高患者的免疫力，对于卵巢癌术后化疗的患者有重要意义。

Abstract

Background In recent years, the number of ovarian cancer patients has been increasing year by year, and the five-year survival rate is only 20% -30%. Studies have shown that 40% -80% of cancer patients have varying degrees of malnutrition, and about 20% of cancer patients die directly from malnutrition. Only 5% of non subjective weight loss can also lead to a decrease in survival rate. The 5-year survival rate of malnourished tumor patients is significantly lower than that of patients without malnutrition. Therefore, improving nutritional management for postoperative ovarian cancer patients is crucial. Objective To explore the role of EN in improving gastrointestinal function and enhancing the immune system of postoperative chemotherapy patients with ovarian cancer. As a result, enteral nutrition support therapy can improve the body measurements, biochemical indicators, immune function, and reduce chemotherapy side effects in patients with ovarian cancer undergoing postoperative chemotherapy. Therefore, timely EN treatment can enhance the patient's immune and nutritional status, improve their quality of life and survival rate, and prevent the occurrence of chemotherapy toxic side effects and other complications, which has a very positive and important significance for the prognosis of cancer patients.
Conclusion   EN treatment can improve patients' gastrointestinal function and enhance their immunity, which is of great significance for patients with ovarian cancer undergoing postoperative chemotherapy.