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Open Access Article

Contemporary Nursing. 2025; 6: (1) ; 1-7 ; DOI: 10.12208/j.cn.20250001.

Qualitative study on the occurrence of low anterior rectal resection syndrome after bowel resection in patients with ovarian cancer and analysis of its changing characteristics
卵巢癌患者肠切除术后低位直肠前切除综合征发生情况调查及变化特征 分析的质性研究

作者: 徐小雨 *, 沈静, 王珺

复旦大学附属肿瘤医院护理部,复旦大学上海医学院肿瘤学系 上海

*通讯作者: 徐小雨,单位:复旦大学附属肿瘤医院护理部,复旦大学上海医学院肿瘤学系 上海;

发布时间: 2025-01-13 总浏览量: 106

摘要

目的 深入调查卵巢癌患者肠切除术后低位直肠前切除综合征的症状体验,旨在为后续提出针对性症状管理的干预措施提供参考。方法 采用描述性质性方法进行研究,目的性抽样选取了11名卵巢癌低位直肠前切除术后患者并进行回顾性半结构式深入访谈,收集资料,采用内容分析法分析资料,并形成主题。结果 调查提示:中文版低位直肠前切综合征评分表提示术后一个月、术后三个月、术后六个月的LARS得分显著大于术前的得分。通过深入访谈共提炼出4个主题和7个次主题,即身体症状体验(大便不尽及排便不禁的困扰、失眠带来的困扰、性功能下降和性渴望欲求不满)、心理症状体验(焦虑与恐惧、症状转归不确定感)、社会支持体验(家庭关系与支持、信息需求、社会交往与融入)、经济负担的加重。结论 理解LARS对患者生活质量的具体影响,了解患者对相关资源的需求,并提升对卵巢癌低位直肠前切除患者术后LARS的发生、恢复情况和影响因素的理解,以实现提升患者生活质量并最终改善患者预后的目标。为下一步构建卵巢癌患者低位直肠前切除术后LARS管理方案提供参考和借鉴。

关键词: 卵巢癌;低位直肠前切综合征;质性研究;护理

Abstract

Objective To conduct an in-depth investigation of the symptom experience of low anterior rectal resection syndrome after bowel resection in patients with ovarian cancer, aiming to provide a reference for the subsequent intervention measures for targeted symptom management.
Methods A descriptive qualitative method was used for the study. Eleven patients who underwent low anterior rectal resection for ovarian cancer were selected by purposive sampling and retrospective semi-structured in-depth interviews were conducted to collect data. Content analysis was used to analyze the data and form themes.
Results The survey suggested that the Chinese version of the low anterior rectal resection syndrome score sheet indicated that the LARS scores at one month, three months, and six months after surgery were significantly higher than those before surgery. Through in-depth interviews, 4 themes and 7 sub-themes were extracted, namely, physical symptom experience (trouble with incomplete defecation and incontinence, trouble caused by insomnia, decreased sexual function and unsatisfied sexual desire), psychological symptom experience (anxiety and fear, uncertainty about symptom outcome), social support experience (family relationship and support, information needs, social interaction and integration), and increased economic burden.
Conclusion   Understand the specific impact of LARS on patients' quality of life, understand patients' needs for relevant resources, and enhance understanding of the occurrence, recovery and influencing factors of LARS after low anterior rectal resection for ovarian cancer, so as to achieve the goal of improving patients' quality of life and ultimately improving patients' prognosis. Provide reference and reference for the next step of constructing a LARS management plan for patients with ovarian cancer after low anterior rectal resection.

Key words: Ovarian cancer; Low anterior rectal resection syndrome; Qualitative research; Nursing

参考文献 References

[1] SIEGEL R L, MILLER K D, JEMAL A. Cancer statistics, 2018[J]. CA Cancer J Clin, 2018,68(1): 7-30. 

[2] BRAY F, FERLAY J, SOERJOMATARAM I, et al. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries[J]. CA Cancer J Clin, 2018,68(6): 394-424.

[3] TORRE L A, TRABERT B, DESANTIS C E, et al. Ovarian cancer statistics, 2018[J]. CA Cancer J Clin, 2018,68(4): 284-296. 

[4] DOTTINO J A, HE W, SUN C C, et al. National trends in bowel and upper abdominal procedures in ovarian cancer surgery[J]. Int J Gynecol Cancer, 2020,30(8): 1195-1202. 

[5] BACALBASA N, BALESCU I, DIACONU C, et al. Right Upper Abdominal Resections in Advanced Stage Ovarian Cancer[J]. In Vivo, 2020,34(3): 1487-1492.

[6] 周颖, 朱晨辰, 张天骄, 等. 卵巢癌肿瘤细胞减灭术行肠切除术后并发肠瘘的临床观察[J]. 现代妇产科进展, 2020,29(09): 641-645. 

[7] JAEGER W, ACKERMANN S, KESSLER H, et al. The effect of bowel resection on survival in advanced epithelial ovarian cancer[J]. Gynecol Oncol, 2001,83(2): 286-291. 

[8] 刘亚婷,谢玲女,蒋丽丽,等. 基于潜变量增长模型的直肠癌低位前切除患者术后症状发展轨迹研究[J]. 护理康复,2023,22(2):1-6.

[9] BRANNSTROM F, BJERREGAARD J K, WINBLADH A, et al. Multidisciplinary teamco nferences promote treatment according to guidelines in rectal cancer[J]. Acta Oncol,2015,54(4):447-453.

[10] 刘京,朱蓓,魏青,等. 直肠癌低位前切除综合征预防及管理的证据总结[J]. 现代临床护理,2023,22(2):77-84. 

[11] TRENTI  L,GALVEZ  A,BIONDO S , et al.  Quality of life and anteriorresection syndrome after surgery for mid to low rectal cancer: a cross-sectional study[J]. EurJ SurgOncol , 2018,44(7):1031-1039.

[12] CHEN T Y,WILTINK L M,NOUT R A,et al. Bowel func- tion 14 years after preoperative short -course radiotherapy and total mesorectal excision for rectal cancer:report of a  multicenter randomized trial[J].Clin Colorectal Cancer, 2015,14(2):106-114.

[13] THOMAS G,VAN H M,VANDER H J,et al. Awareness and management of low anterior resection syndrome: a Dutch national survey among colorectal surgeons and spe-cialized nurses[J]. EurJ Surg Oncol,2019,45(2):174-179.

[14] EMMERTSEN K J, LAURBERG S. Low anterior resection syndrome score: development and validation of a symptom-based scoring system for bowel dysfunction after low anterior resection for rectal cancer[J]. Annals of Surgery, 2012, 255(5): 922-928.

[15] Remes-Troche JM, De-Ocampo S, Valestin J, et al. Rectoanal reflexes and sensorimotor response in rectal hyposensitivity[J]. Dis Colon Rectum,2010,53(7):1047-1054. 

[16] Myers PL, Krasniak PJ, Day SJ, et al. Gluteal flaps revisited: technical modifications for perineal wound reconstruc-tion[J]. Ann Plast Surg,2019,82(6):667-670. 

[17] Liu W, Xia HO. Can I control my bowel symptoms myself? The experience of controlling defaecation dysfunction among patients with rectal cancer after sphincter-saving surgery:a qualitative study[J]. Int J Qual Stud Health Well-being,2022,17(1):2031832.

[18] Christensen P, Im Baeten C, Espín-Basany E, et al. Management guidelines for low anterior resection syndrome-the MANUEL project[J]. Colorectal Dis,2021, 23(2): 461-475. 

[19] Pieri C, Patton V. Clinical nursing management of low anterior resection syndrome-a practical guide to understanding and managing symptoms[J]. J Stomal Therapy Australia,2020,40(2). 

[20] Sun R, Dai ZY, Zhang Y, et al. The incidence and risk factors of low anterior resection syndrome(LARS) after sphincter-preserving surgery of rectal cancer: a systematic review and meta-analysis[J]. Support Care Cancer,2021, 29(12): 7249-7258.

[21] Dul skas A, Smolskas E, Kildusiene I,et al. Treatment possibilities for low anterior resection syndrome: a review of the literature[J]. Int J Colorectal Dis,2018,33(3):251-260.

[22] Nakagawa H,Sasai H,Tanaka K. Defecation dysfunction and exercise habits among survivors of rectal cancer:a pilot qualitative study[J]. Healthcare(Basel),2022,10(10):2029. 

[23] Pape E, Decoene E, Debrauwere M, et al. Information and counselling needs of patients with major low anterior resection syndrome: a qualitative study[J]. J Clin Nurs, 2023, 32(7-8): 1240-1250. 

[24] 庞雪滢,胡少华,李慧,等. 直肠癌患者低位前切除综合征症状管理平台的开发及可用性评价[J]. 中国护理管理, 2022, 22(3):445-449. Pang XY,Hu SH,Li H,et al. Development and usability evaluation of syndrome management platform for Low Anterior Resection Syndrome inpatients with rectal cancer[J]. Chin NursManag,2022,22(3):445-449.

[25] Garfinkle R, Wong-Chong N, Petrucci A, et al. Assessing the readability, quality and accuracy of online health information for patients with low anterior resection syndrome following surgery for rectal cancer[J]. Colorectal Dis,2019,21(5):523-531.

[26] Sun XC, Zhong WF, Lu JJ,et al. Influence of psychological nursing intervention on psychological state, treatment compliance, and immune function of postoperative patients   with rectal cancer[J].J Oncol,2021,2021:1071490. 

[27] 王磊,蒋晓莲.叙事研究-护理质性研究的新方法. 中华护理杂志,2006,4(4):352-354.

[28] Clayton A H, Hamilton D V. Female sexual dysfunction. Psychiatr Clin North Am,2010,33(2):323-338.

[29] 高青青. 全子宫切除术后延续性护理对患者性生活质量影响的研究进展[J]. 现代护理医学杂志,2023,2(1). 

引用本文

徐小雨, 沈静, 王珺, 卵巢癌患者肠切除术后低位直肠前切除综合征发生情况调查及变化特征 分析的质性研究[J]. 当代护理, 2025; 6: (1) : 1-7.