摘要
目的 观察心理干预配合米索前列醇片预防高危人群中期妊娠引产产后出血的临床疗效。方法 选取本院2020年5月至2022年4月妇科收治的高危中期妊娠引产患者120例，随机分为对照组和观察组各60例，统计中期引产后2 h内的出血量和24 h内产妇的出血量及急诊清宫率。结果 观察组引产后2h内和24h内的平均出血量及急诊清宫率均较对照组显著减少，且两组间比较差异有统计学意义（P＜0.05）。2组治疗前焦虑、抑郁评分对比差异较小，无统计学意义（P＞0.05）。治疗后观察组的焦虑、抑郁评分较低（P＜0.05）。且各组治疗前后比较差异明显（P＜0.05）。观察组满意度明显要高于对照组（P＜0.05）。结论 心理干预配合米索前列醇片预防高危人群中期妊娠引产可明显减少引产后的出血量，减少急诊清宫率，且不良反应少，安全性高。
关键词： 心理干预；米索前列醇片；中期妊娠
Abstract
Objective To observe the clinical efficacy of psychological intervention combined with misoprostol tablets in preventing postpartum hemorrhage during induced labor in high-risk population. Methods One hundred and twenty patients with high risk mid-term pregnancy induced labor admitted by the department of gynecology in our hospital from May 2020 to April 2022 were randomly divided into the control group and the observation group, with 60 cases in each group. The amount of bleeding within 2 hours after mid-term induced labor, the amount of bleeding within 24 hours after mid-term induced labor and the rate of emergency uterine clearance were counted. Results The average amount of bleeding within 2 hours and 24 hours after induction of labor and the rate of emergency uterine clearance in the observation group were significantly lower than those in the control group, and the difference between the two groups was statistically significant (P<0.05). There was no significant difference in anxiety and depression scores between the two groups before treatment (P>0.05). After treatment, the anxiety and depression scores of the observation group were lower (P<0.05). There was significant difference in each group before and after treatment (P<0.05). The satisfaction of the observation group was significantly higher than that of the control group (P<0.05). Conclusion Psychological intervention combined with misoprostol tablets can significantly reduce the amount of bleeding after induction of labor, reduce the rate of emergency uterine clearance, and have less adverse reactions and high safety.
Key words： Psychological intervention; Misoprostol tablets; Mid-term pregnancy
参考文献 References
[1] 段嫄,罗柳芳,余海霞. 激励式心理护理配合放松训练在中期妊娠乳酸依沙吖啶引产患者中的应用效果[J]. 护理实践与研究,2018,21:67-69.
[2] 姜菊.米非司酮配伍米索前列醇和缩宫素联合应用预防中期妊娠引产出血的效果观察[J].中外女性健康研究,2016,7(39):36.
[3] 陈艳艳.计划生育手术中的药物应用[J].家庭心理医生,2015,11(3):251.
[4] 滕妹芳.12例中期引产妊娠出血原因分析及护理[J].大家健康(学术版),2014,18:204-275.
[5] 马飞雕,郭春光. 依沙吖啶联合米非司酮和米索前列醇在中期妊娠引产中的应用效果观察[J]. 中国实用医药,2021,26:128-130.
[6] 张建香.心理护理配合米索前列醇合并缩宫素治疗妊娠中期引产后出血的临床观察[J].科技与创新.2015.09.132
[7] 涂贤秀. 米索前列醇联合缩宫素预防中期妊娠引产后出血的临床观察[J]. 中外医学研究, 2012 10(17): 35-36
[8] 盛青菁,王蓓颖,车映,等.中期妊娠羊膜腔内注射依沙吖啶引产出血的高危因素[J].同济大学学报(医学版), 2019, 3:370-375.
[9] 孙玥,葛辉.宫颈注射缩宫素与舌下含化米素前列醇片联合治疗中期妊娠引产产后出血的效果观察[J].临床医学研究与实践,2017,23:66-67.
[10] 石晓英.米非司酮配伍米索前列醇和缩宫素联合应用预防中期妊娠引产出血的临床效果[J].世界最新医学信息文摘, 2017(04):124.
[11] 姜菊.米非司酮配伍米索前列醇和缩宫素联合应用预防中期妊娠引产出血的效果观察[J].中外女性健康研究, 2016(7):2.
[12] 段红艳.米非司酮配合小剂量米索前列醇片在中期妊娠引产中的效果观察[J].中文科技期刊数据库(全文版)医药卫生, 2022(10):4.
[13] 蒲玲珍.分析米非司酮配伍米索前列醇在终止中期妊娠的应用价值[J].河南外科学杂志, 2017, 23(2):2.
[14] 陈倩,房芳,冯宝双,等.米非司酮配伍米索前列醇终止中期妊娠的综合护理干预效果[J].心电图杂志：电子版, 2019(1):2.
[15] 张蕾龙千里姬芝栩罗小英田程淮.超声引导侧卧位注射利凡诺联合米索前列醇在未成年中期妊娠引产中的运用[J].临床医药实践, 2018, 027(009):675-678.