摘要
目的 本次研究主要分析低钠血症与慢性充血性心力衰竭预后之间的关系。方法 本次该项研究的样本总计120例,研究时间2019年5月到2020年12月,按照患者入院时的血清钠水平分为两组,血清钠水平低于135mmol/L作为低钠组(n=40),血清钠水平≥135mmol/L作为正常组(n=80),分析低钠血症与心衰严重程度的关系、预后效果。结果 低钠组患者的B型钠尿肽、左心室舒张末期内径高于正常组,左心室射血分数比正常组低;低钠组患者的未缓解出院率、死亡率均高于正常组(P<0.05)。结论 慢性充血性心力衰竭合并低血症患者则表明预后不良,应该及时采取有效的治疗措施,及时纠正低钠血症,对提高患者的生存率,改善预后效果具有十分重要的意义。
关键词: 低钠血症;慢性充血性心力衰竭;预后关系
Abstract
Objective: This study mainly analyzed the relationship between hyponatremia and the prognosis of chronic congestive heart failure. Methods: For a total sample of 120 patients from May 2019 to December 2020, the serum sodium level of patients on admission was divided into two groups. The serum sodium level below 135 mmol/L was low-sodium group (n=40), and the serum sodium level was 135 mmol/L as normal group (n=80) to analyze the relationship between hyponatremia and heart failure severity, and the prognostic effect. Results: Type B peptide in the low sodium group had higher end diastolic diameter than the normal group, and left ventricular ejection fraction was lower than the normal group; the discharge rate was higher than the normal group (P <0.05). Conclusion : Patients with chronic congestive heart failure and hypoaemia show poor prognosis, and effective treatment measures should be taken to correct hyponatremia, which is of great significance to improve the survival rate of patients and improve the prognostic effect.
Key words: Hyponatremia; Chronic Congestive Heart Failure; Prognosis Relationship
参考文献 References
[1] 赵秋燕,杨瑛,陈章荣,等.西南地区慢性心力衰竭患者合并低钠血症的临床特征[J].岭南心血管病杂志,2019, 25(3):322-326.
[2] 汤辉,陈彪,王春梅,等.低钠血症与老年急危重病临床[J].医学综述,2017,23(4):660-664.
[3] 岳华.低钠血症对心衰患者生存状况的影响及其相关因素分析[J].医学临床研究,2017,34(6):1231-1233.
[4] 王晓垒.低钠血症与慢性心力衰竭的相关性分析[J].中国实用医药,2016,11(26):118-119.
[5] 温红静,王世国,张汉青.低钠血症对心力衰竭患者生存预后的影响及相关因素分析[J].当代医学,2020, 26(10):28-31.
[6] 张金瑞,史丹,于治利,张东华,张金波.慢性心力衰竭患者合并低钠血症的治疗方法及治疗效果[J].世界最新医学信息文摘,2017,17(51):76+80.
[7] 韩忠书,王灵君,岳满夏,丁秀娟,王静杰.低钠血症对心力衰竭患者心功能影响研究[J].吉林医学,2017, 38(04): 614-615.
[8] 庞关义.慢性充血性心力衰竭合并低钠血症患者的临床治疗及发病机制[J].河北医药,2013,(23): 3577- 3578 . DOI:10.3969/j.issn.1002-7386.2013.23.025.