Application of proton pump inhibitor combined with sulfamethoxazole in the treatment of upper gastrointestinal bleeding
质子泵抑制剂联合酚磺乙胺治疗上消化道出血护理的应用

摘要

目的 研究上消化道出血护理采取质子泵抑制剂、酚磺乙胺一同治疗后产生的效果。方法 研究对象：70例上消化道出血患者。研究时间：2020年2月到2021年2月。研究分组方式：随机数表方式。研究分组类别：对照组实施单独质子泵抑制剂治疗，为35例。观察组加入酚磺乙胺治疗，为35例。研究根本目的：对比两组治疗后临床效果、临床指标、治疗前后凝血指标变化以及不良反应发生率。结果 和对照组相比较，观察组治疗总有效率明显较高，临床指标情况明显较好，凝血功能明显改善，（P<0.05）为差异显著，有统计学意义。对照组和观察组不良反应发生率无明显差异，（P＞0.05）。结论 上消化道出血护理采取质子泵抑制剂、酚磺乙胺一同治疗能够改善患者凝血功能，治疗效果较明显，并且治疗安全性也较高，值得临床重视。

Abstract

Objective: To study the effect of proton pump inhibitor and etamsylate on upper gastrointestinal bleeding.
Methods: Subjects: 70 patients with upper gastrointestinal bleeding. Research time: February 2020 to February 2021. Study grouping: random number table. Study grouping category: 35 cases in the control group were treated with proton pump inhibitors alone. 35 cases in the observation group were treated with etamsylate. Basic objective: To compare the clinical effect, clinical indexes, changes of coagulation indexes before and after treatment and the incidence of adverse reactions between the two groups.
Results: compared with the control group, the total effective rate of the observation group was significantly higher, the clinical indicators were significantly better, and the coagulation function was significantly improved (p<0.05). There was no significant difference in the incidence of adverse reactions between the control group and the observation group (P > 0.05).
Conclusion  : Proton pump inhibitor and etamsylate can improve the coagulation function of patients with upper gastrointestinal bleeding. The treatment effect is obvious, and the treatment safety is also high, which is worthy of clinical attention.